靶标:
TSPAN8
产品别名:
CO-029; TM4SF3; TSPAN8; tetraspanin 8; tetraspanin 8; tetraspanin-8; transmembrane 4 superfamily member 3; tspan-8; tumor-associated antigen CO-029; TM4SF3蛋白; 跨膜蛋白4超家族成员3;
背景信息:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008],