靶标:
UBE2G1
产品别名:
E217K; UBC7; UBE2G; UBE2G1; ubiquitin conjugating enzyme E2 G1; ubiquitin conjugating enzyme E2 G1; ubiquitin-conjugating enzyme E2 G1; E2 ubiquitin-conjugating enzyme G1; ubiquitin carrier protein G1; ubiquitin conjugating enzyme E2G 1; ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans); ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2G 1 (homologous to C. elegans UBC7); ubiquitin-protein ligase G1; 泛素蛋白连接酶G1;
背景信息:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008],