靶标：
UQCRB
产品别名：
MC3DN3； QCR7； QP-C； QPC； UQBC； UQBP； UQCR6； UQPC； UQCRB； ubiquinol-cytochrome c reductase binding protein； ubiquinol-cytochrome c reductase binding protein； cytochrome b-c1 complex subunit 7； complex III subunit 7； complex III subunit VII； mitochondrial ubiquinone-binding protein； ubiquinol-cytochrome c reductase complex 14 kDa protein； ubiquinol-cytochrome c reductase, complex III subunit VI； 泛醇细胞色素C还原酶结合蛋白(UQCRB)；
背景信息：
This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X.
