靶标:
USF1
产品别名:
FCHL; FCHL1; HYPLIP1; MLTF; MLTFI; UEF; bHLHb11; USF1; upstream transcription factor 1; upstream transcription factor 1; upstream stimulatory factor 1; class B basic helix-loop-helix protein 11; major late transcription factor 1; 等上游刺激因子1;
背景信息:
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. This gene has been linked to familial combined hyperlipidemia (FCHL). Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been defined on chromosome 21. [provided by RefSeq, Feb 2013],