靶标:
VLDLR
产品别名:
CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLRCH; VLDLR; very low density lipoprotein receptor; very low density lipoprotein receptor; very low-density lipoprotein receptor; VLDL receptor; 极低密度脂蛋白受体; 极低密度脂蛋白受体(VLDLR);
背景信息:
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009],