靶标:
ZNF146
产品别名:
OZF; ZNF146; zinc finger protein 146; zinc finger protein 146; zinc finger protein OZF; only zinc finger protein; 锌指蛋白146;
背景信息:
ZNF146 (zinc finger protein 146), also known as OZF (only zinc finger protein), is a 292 amino acid nuclear protein that binds DNA and belongs to the Kr¨1ppel C2H2-type zinc-finger protein family. ZNF146 interacts with UBC9 (ubiquitin carrier protein 9) and RAP1 (repressor/activator protein 1 homolog), and is highly expressed in multiple pancreatic and colorectal cancers. Lower levels of expression have been observed in kidney, lung, placenta and brain.