靶标：
ZNF148
产品别名：
BERF-1； BFCOL1； GDACCF； HT-BETA； ZBP-89； ZFP148； pHZ-52； ZNF148； zinc finger protein 148； zinc finger protein 148； zinc finger protein 148； CACCC box-binding protein； CLL-associated antigen KW-10； transcription factor ZBP-89； zinc finger DNA-binding protein 89； 锌指蛋白148；
背景信息：
The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies.
