靶标:
TRIM26
产品别名:
AFP; RNF95; ZNF173; TRIM26; tripartite motif containing 26; tripartite motif containing 26; tripartite motif-containing protein 26; RING finger protein 95; acid finger protein; widely expressed acid zinc finger protein; zinc finger protein 173; TRIM26蛋白;
背景信息:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene.