靶标：
PRDM2
产品别名：
HUMHOXY1； KMT8； KMT8A； MTB-ZF； RIZ； RIZ1； RIZ2； PRDM2； PR/SET domain 2； PR/SET domain 2； PR domain zinc finger protein 2； GATA-3 binding protein G3B； MTE-binding protein； PR domain 2； PR domain containing 2, with ZNF domain； PR domain-containing protein 2； lysine N-methyltransferase 8； retinoblastoma protein-binding zinc finger protein； retinoblastoma protein-interacting zinc finger protein； zinc finger protein RIZ； zinc-finger DNA-binding protein； 锌指蛋白RIZ1；
背景信息：
This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
