靶标：
KCNAB1
产品别名：
AKR6A3； KCNA1B； KV-BETA-1； Kvb1.3； hKvBeta3； hKvb3； KCNAB1； potassium voltage-gated channel subfamily A regulatory beta subunit 1； potassium voltage-gated channel subfamily A regulatory beta subunit 1； voltage-gated potassium channel subunit beta-1； K(+) channel subunit beta-1； K+ channel Beta1a chain； potassium channel beta 3 chain； potassium channel beta3 subunit； potassium channel shaker chain beta 1a； potassium channel, voltage gated subfamily A regulatory beta subunit 1； potassium voltage-gated channel subfamily A member regulatory beta subunit 1； potassium voltage-gated channel, shaker-related subfamily, beta member 1； 电压门控钾通道蛋白1；
背景信息：
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member includes distinct isoforms which are encoded by alternatively spliced transcript variants of this gene. Some of these isoforms are beta subunits, which form heteromultimeric complexes with alpha subunits and modulate the activity of the pore-forming alp
