靶标：
HSD17B8
产品别名：
D6S2245E； FABG； FABGL； H2-KE6； HKE6； KE6； RING2； SDR30C1； dJ1033B10.9； HSD17B8； hydroxysteroid 17-beta dehydrogenase 8； hydroxysteroid 17-beta dehydrogenase 8； (3R)-3-hydroxyacyl-CoA dehydrogenase； 17-beta-HSD 8； 17-beta-hydroxysteroid dehydrogenase 8； 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit； 3-oxoacyl-[acyl-carrier-protein] reductase； KAR alpha subunit； estradiol 17-beta-dehydrogenase 8； estrogen 17-oxidoreductase； ke-6； protein Ke6； really interesting new gene 2 protein； short chain dehydrogenase/reductase family 30C member 1； testosterone 17-beta-dehydrogenase 8； 羟类固醇脱氢酶17β；
背景信息：
hydroxysteroid 17-beta dehydrogenase 8(HSD17B8) Homo sapiens In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008],
