靶标:
NELFE
产品别名:
D6S45; NELF-E; RD; RDBP; RDP; NELFE; negative elongation factor complex member E; negative elongation factor complex member E; negative elongation factor E; RD RNA-binding protein; RNA-binding protein RD; major histocompatibility complex gene RD; negative elongation factor polypeptide E; nuclear protein; 转录延伸因子E;
背景信息:
The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6.