靶标:
CSRP3
产品别名:
CLP; CMD1M; CMH12; CRP3; LMO4; MLP; CSRP3; cysteine and glycine rich protein 3; cysteine and glycine rich protein 3; cysteine and glycine-rich protein 3; LIM domain only 4; cardiac LIM domain protein; cysteine and glycine-rich protein 3 (cardiac LIM protein); 富含半胱氨酸蛋白3;
背景信息:
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.