靶标：
PTP4A2
产品别名：
HH13； HH7-2； HU-PP-1； OV-1； PRL-2； PRL2； PTP4A； PTPCAAX2； ptp-IV1a； ptp-IV1b； PTP4A2； protein tyrosine phosphatase 4A2； protein tyrosine phosphatase 4A2； protein tyrosine phosphatase type IVA 2； PTP(CAAXII)； phosphatase of regenerating liver 2； protein tyrosine phosphatase IVA； protein tyrosine phosphatase IVA2； protein tyrosine phosphatase type IVA, member 2； protein-tyrosine phosphatase of regenerating liver 2； 肝再生磷酸酯酶2； 蛋白酪氨酸磷酸酶ⅣA2(PTP4A2)；
背景信息：
protein tyrosine phosphatase type IVA, member 2(PTP4A2) Homo sapiens The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010],
