靶标:
GAN
产品别名:
GAN1; GIG; KLHL16; GAN; gigaxonin; gigaxonin; gigaxonin; epididymis secretory sperm binding protein; kelch-like family member 16; kelch-like protein 16; 巨轴索神经病蛋白GAN; 巨轴索神经蛋白(GAN);
背景信息:
This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN).