靶标:
FZD4
产品别名:
CD344; EVR1; FEVR; FZD4S; Fz-4; Fz4; FzE4; GPCR; hFz4; FZD4; frizzled class receptor 4; frizzled class receptor 4; frizzled-4; WNT receptor frizzled-4; frizzled 4, seven transmembrane spanning receptor; frizzled family receptor 4; frizzled homolog 4; 卷曲同源物4(FZD4);
背景信息:
frizzled class receptor 4(FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008],