靶标：
FZD7
产品别名：
FzE3； FZD7； frizzled class receptor 7； frizzled class receptor 7； frizzled-7； Frizzled, drosophila, homolog of, 7； frizzled 7, seven transmembrane spanning receptor； frizzled family receptor 7； frizzled homolog 7； fz-7； hFz7； 卷曲蛋白FZD7；
背景信息：
frizzled class receptor 7(FZD7) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008],
