靶标:
KLF11
产品别名:
FKLF; FKLF1; MODY7; TIEG2; Tieg3; KLF11; KLF transcription factor 11; KLF transcription factor 11; Krueppel-like factor 11; Kruppel like factor 11; TGFB-inducible early growth response protein 2; TIEG-2; transforming growth factor-beta-inducible early growth response protein 2; FKLF蛋白;
背景信息:
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],