靶标:
SEMA7A
产品别名:
CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; PFIC11; SEMAK1; SEMAL; SEMA7A; semaphorin 7A (John Milton Hagen blood group); semaphorin 7A (John Milton Hagen blood group); semaphorin-7A; JMH blood group antigen; John Milton Hagen blood group H-Sema K1; john-Milton-Hargen human blood group Ag; sema K1; sema L; sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (JMH blood group); sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 7A; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); semaphorin-K1; semaphorin-L; 信号素7A(SEMA7A); 轴突生长因子CD108;
背景信息:
This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],