靶标：
API5
产品别名：
AAC-11； AAC11； API5； apoptosis inhibitor 5； apoptosis inhibitor 5； apoptosis inhibitor 5； FIF； antiapoptosis clone 11 protein； cell migration-inducing gene 8 protein； fibroblast growth factor 2-interacting factor 2； migration-inducing protein MIG8； 凋亡抑制因子5； 凋亡抑制因子5(API5)；
背景信息：
This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011],
