靶标:
DENR
产品别名:
DRP; DRP1; SMAP-3; DENR; density regulated re-initiation and release factor; density regulated re-initiation and release factor; density-regulated protein; smooth muscle cell associated protein-3; 密度调节蛋白;
背景信息:
This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants.