靶标:
THOC5
产品别名:
C22orf19; Fmip; PK1.3; fSAP79; THOC5; THO complex 5; THO complex 5; THO complex subunit 5 homolog; Fms-interacting protein; NF2/meningioma region protein pK1.3; PP39.2; functional spliceosome-associated protein 79; hTREX90; placental protein 39.2; 转录因子THOC5;
背景信息:
function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,