靶标:
NPFF
产品别名:
FMRFAL; NPFF; neuropeptide FF-amide peptide precursor; neuropeptide FF-amide peptide precursor; pro-FMRFamide-related neuropeptide FF; 吗啡痛觉调节肽NPFF; 神经肽FF(NPFF);
背景信息:
This gene encodes a member of the FMRFamide related peptide (FARP) family of neuropeptides. The encoded preproprotein is proteolytically processed to generate multiple amidated peptides. These peptides may play a role in the regulation of heart rate and blood pressure and the modulation of morphine-induced antinociception. Patients with hypertension exhibit decreased expression of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.