靶标:
UNC5C
产品别名:
UNC5H3; UNC5C; unc-5 netrin receptor C; unc-5 netrin receptor C; netrin receptor UNC5C; protein unc-5 homolog 3; protein unc-5 homolog C; unc-5 homolog 3; unc-5 homolog C; unc5 (C.elegans homolog) c; 神经突起生长诱导因子受体UNC5C;
背景信息:
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008],