靶标:
OASL
产品别名:
OASL1; OASLd; TRIP-14; TRIP14; p59 OASL; p59-OASL; p59OASL; OASL; 2'-5'-oligoadenylate synthetase like; 2'-5'-oligoadenylate synthetase like; 2'-5'-oligoadenylate synthase-like protein; 2'-5'-OAS-RP; 2'-5'-OAS-related protein; 59 kDa 2'-5'-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein; TR-interacting protein 14; thyroid receptor-interacting protein 14; 2',5'-寡腺苷酸合成酶样蛋白(OASL); 甲状腺受体相互作用蛋白14;
背景信息:
caution:This may not be the true ortholog of mouse OASL.,function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,similarity:Contains 2 ubiquitin-like domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.,tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.,