靶标:
EIF3D
产品别名:
EIF3S7; eIF3-p66; eIF3-zeta; EIF3D; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D; eIF3 p66; eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; translation initiation factor eIF3 p66 subunit; EIF3D蛋白;
背景信息:
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008],