靶标:
MARCO
产品别名:
SCARA2; SR-A6; MARCO; macrophage receptor with collagenous structure; macrophage receptor with collagenous structure; macrophage receptor MARCO; scavenger receptor class A, member 2; 巨噬细胞清道夫受体; 胶原结构巨噬细胞受体(MARCO);
背景信息:
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008],