靶标:
ADAM19
产品别名:
FKSG34; MADDAM; MLTNB; ADAM19; ADAM metallopeptidase domain 19; ADAM metallopeptidase domain 19; disintegrin and metalloproteinase domain-containing protein 19; a disintegrin and metalloproteinase domain 19 (meltrin beta); metalloprotease and disintegrin dendritic antigen marker; metalloprotease-disintegrin meltrin beta; 去整合素样金属蛋白酶19; 解整合素金属蛋白酶19(ADAM19);
背景信息:
ADAM metallopeptidase domain 19(ADAM19) Homo sapiens This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimer's disease. [provided by RefSeq, May 2013],