靶标：
ADAM15
产品别名：
MDC15； ADAM15； ADAM metallopeptidase domain 15； ADAM metallopeptidase domain 15； disintegrin and metalloproteinase domain-containing protein 15； MDC-15； a disintegrin and metalloproteinase domain 15 (metargidin)； metalloprotease RGD disintegrin protein； metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15； 去整合素样金属蛋白酶15； 解整合素金属蛋白酶15(ADAM15)；
背景信息：
ADAM metallopeptidase domain 15(ADAM15) Homo sapiens The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
