靶标：
SIGLEC5
产品别名：
CD170； CD33L2； OB-BP2； OBBP2； SIGLEC-5； SIGLEC5； sialic acid binding Ig like lectin 5； sialic acid binding Ig like lectin 5； sialic acid-binding Ig-like lectin 5； CD33 antigen-like 2； OB-binding protein 2； obesity-binding protein 2； sialic acid-binding immunoglobulin-like lectin 5； 唾液酸结合Ig样凝集素5(SIGLEC5)； 唾液酸结合性免疫球蛋白样凝集素5；
背景信息：
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012],
