靶标：
TSC22D1
产品别名：
Ptg-2； TGFB1I4； TSC22； TSC22D1； TSC22 domain family member 1； TSC22 domain family member 1； TSC22 domain family protein 1； TGFB-stimulated clone 22 homolog； TGFbeta-stimulated clone 22； cerebral protein 2； regulatory protein TSC-22； transcriptional regulator TSC-22； transforming growth factor beta-1-induced transcript 4 protein； transforming growth factor beta-stimulated protein TSC-22；
背景信息：
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],
