靶标：
WASF1
产品别名：
NEDALVS； SCAR1； WAVE； WAVE1； WASF1； WASP family member 1； WASP family member 1； wiskott-Aldrich syndrome protein family member 1； WAS protein family member 1； WASP family protein member 1； homology of dictyostelium scar 1； protein WAVE-1； verprolin homology domain-containing protein 1； 富含脯氨酸同源蛋白1；
背景信息：
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
