靶标:
CHRNA6
产品别名:
CHNRA6; CHRNA6; cholinergic receptor nicotinic alpha 6 subunit; cholinergic receptor nicotinic alpha 6 subunit; neuronal acetylcholine receptor subunit alpha-6; acetylcholine receptor, nicotinic, alpha 6 (neuronal); cholinergic receptor, nicotinic alpha 6; cholinergic receptor, nicotinic, alpha 6 (neuronal); cholinergic receptor, nicotinic, alpha polypeptide 6; 烟碱型乙酰胆碱受体α6/AChRα6;
背景信息:
This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence. [provided by RefSeq, Dec 2010],