靶标：
RNF8
产品别名：
hRNF8； RNF8； ring finger protein 8； ring finger protein 8； E3 ubiquitin-protein ligase RNF8； C3HC4-type zinc finger protein； RING-type E3 ubiquitin transferase RNF8； UBC13/UEV-interacting ring finger protein； ring finger protein (C3HC4 type) 8； ring finger protein 8, E3 ubiquitin protein ligase； 环指蛋白8；
背景信息：
Mediates the ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53BP1 and BRCA1 ionizing radiation-induced foci (IRIF). Promotes the formation of 'Lys-63'-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBE2N/UBC13.
