靶标:
AIP
产品别名:
ARA9; FKBP16; FKBP37; PITA1; SMTPHN; XAP-2; XAP2; AIP; aryl hydrocarbon receptor interacting protein; aryl hydrocarbon receptor interacting protein; AH receptor-interacting protein; Ah receptor activated 9; FK506-binding protein 37; FKBP prolyl isomerase 16; HBV X-associated protein 2; X-associated protein-2; aryl hydrocarbon receptor-associated protein 9; hepatitis B virus X-associated cellular protein 2; immunophilin homolog ARA9; 乙型肝炎病毒X相关蛋白2; 芳香烃受体相互作用蛋白(AIP);
背景信息:
The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014],