靶标:
DIRAS3
产品别名:
ARHI; NOEY2; DIRAS3; DIRAS family GTPase 3; DIRAS family GTPase 3; GTP-binding protein Di-Ras3; DIRAS family, GTP-binding RAS-like 3; distinct subgroup of the Ras family member 3; ras homolog gene family, member I; rho-related GTP-binding protein RhoI; 抑癌基因ras同源家族1;
背景信息:
This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex. [provided by RefSeq, Nov 2015],