靶标:
PRPF4
产品别名:
HPRP4; HPRP4P; PRP4; Prp4p; RP70; SNRNP60; PRPF4; pre-mRNA processing factor 4; pre-mRNA processing factor 4; U4/U6 small nuclear ribonucleoprotein Prp4; PRP4 homolog; PRP4 pre-mRNA processing factor 4 homolog; PRP4/STK/WD splicing factor; U4/U6 snRNP 60 kDa protein; WD splicing factor Prp4;
背景信息:
The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene.