靶标：
RABEP1
产品别名：
RAB5EP； RABPT5； RABEP1； rabaptin, RAB GTPase binding effector protein 1； rabaptin, RAB GTPase binding effector protein 1； rab GTPase-binding effector protein 1； neurocrescin； rabaptin-4； rabaptin-5； rabaptin-5alpha； renal carcinoma antigen NY-REN-17； RABEP1蛋白；
背景信息：
function:Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.,PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity.,similarity:Belongs to the rabaptin family.,subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.,
