靶标:
NUMBL
产品别名:
CAG3A; CTG3a; NBL; NUMB-R; NUMBLIKE; NUMBR; TNRC23; NUMBL; NUMB like endocytic adaptor protein; NUMB like endocytic adaptor protein; numb-like protein; numb homolog-like; numb-related protein; 膜相关蛋白样蛋白NUMBL;
背景信息:
Numb-like (Numbl or Nbl) binds Notch and is an intracellular modulator of Notch signaling pathway. Numbl contains a phosphotyrosine binding (PTB) domain that could bind the Y682 motif present in the cytoplasmic tail of APP. Deduced molecular weight of Numbl is 72 kDa.