靶标:
BCL7B
产品别名:
SMARCJ2; BCL7B; BAF chromatin remodeling complex subunit BCL7B; BAF chromatin remodeling complex subunit BCL7B; B-cell CLL/lymphoma 7 protein family member B; B-cell CLL/lymphoma 7B; BCL tumor suppressor 7B; BCL7B, BAF complex component; BCL7B蛋白;
背景信息:
This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2010],