靶标：
SOCS6
产品别名：
CIS-4； CIS4； HSPC060； SOCS-4； SOCS-6； SOCS4； SSI4； STAI4； STATI4； SOCS6； suppressor of cytokine signaling 6； suppressor of cytokine signaling 6； suppressor of cytokine signaling 6； STAT induced STAT inhibitor-4； cytokine-inducible SH2 protein 4； suppressor of cytokine signaling 4； 细胞因子信号传导抑制蛋白6；
背景信息：
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
