靶标:
HMGN3
产品别名:
PNAS-24; PNAS-25; TRIP7; HMGN3; high mobility group nucleosomal binding domain 3; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; TR-interacting protein 7; thyroid hormone receptor interacting protein 7; 高迁移率族蛋白N3;
背景信息:
Thyroid hormone receptors are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. The protein encoded by this gene binds thyroid hormone receptor beta, but only in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates.