靶标:
GTF3C4
产品别名:
KAT12; TF3C-delta; TFIII90; TFIIIC290; TFIIIC90; TFIIICDELTA; GTF3C4; general transcription factor IIIC subunit 4; general transcription factor IIIC subunit 4; general transcription factor 3C polypeptide 4; TFIIIC 90 kDa subunit; general transcription factor 3C 4; general transcription factor IIIC, polypeptide 4, 90kDa; transcription factor IIIC 90 kDa subunit; transcription factor IIIC subunit delta; 通用转录因子3C多肽4/TFIIIC90;
背景信息:
catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the TFIIIC subunit 4 family.,subunit:Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6. Interacts with BRF1, GTF3C1, GTF3C2, GTF3C5, GTF3C6, POLR3C and POLR3F.,