靶标：
UBE4A
产品别名：
E4； NEDHMS； UBOX2； UFD2； UBE4A； ubiquitination factor E4A； ubiquitination factor E4A； ubiquitin conjugation factor E4 A； RING-type E3 ubiquitin transferase E4 A； ubiquitination factor E4A (UFD2 homolog, yeast)；
背景信息：
This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011],
