靶标：
HAND1
产品别名：
Hxt； Thing1； bHLHa27； eHand； HAND1； heart and neural crest derivatives expressed 1； heart and neural crest derivatives expressed 1； heart- and neural crest derivatives-expressed protein 1； class A basic helix-loop-helix protein 27； extraembryonic tissues, heart, autonomic nervous system and neural crest derivatives-expressed protein 1； 心脏和神经嵴衍生蛋白1； 心脏神经嵴衍生物表达蛋白1(HAND1)；
背景信息：
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008],
