靶标:
GGPS1
产品别名:
GGPPS; GGPPS1; MDHLO; MUDHLOV; GGPS1; geranylgeranyl diphosphate synthase 1; geranylgeranyl diphosphate synthase 1; geranylgeranyl pyrophosphate synthase; (2E,6E)-farnesyl diphosphate synthase; GGPP synthase; GGPPSase; dimethylallyltranstransferase; farnesyl diphosphate synthase; farnesyltranstransferase; geranyltranstransferase; 异戊二烯基二磷酸合酶1(GGPS1); 法尼基二磷酸合酶1;
背景信息:
This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010],