靶标:
AKAP7
产品别名:
AKAP15; AKAP18; AKAP7; A-kinase anchoring protein 7; A-kinase anchoring protein 7; A-kinase anchoring protein 7; A kinase (PRKA) anchor protein 7; A-kinase anchor protein 18 kDa; A-kinase anchor protein 9 kDa; AKAP 18; 蛋白激酶A锚定蛋白7;
背景信息:
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described.