靶标:
THEMIS2
产品别名:
C1orf38; ICB-1; ICB1; THEMIS2; thymocyte selection associated family member 2; thymocyte selection associated family member 2; protein THEMIS2; basement membrane-induced; induced by contact to basement membrane 1 protein; protein ICB-1; thymocyte-expressed molecule involved in selection protein 2; 1号染色体开放阅读框38;
背景信息:
May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production. Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity.