靶标：
MYOT
产品别名：
LGMD1； LGMD1A； MFM3； TTID； TTOD； MYOT； myotilin； myotilin； myotilin； 57 kDa cytoskeletal protein； myofibrillar titin-like Ig domains protein； titin immunoglobulin domain protein (myotilin)； 肌收缩蛋白MYOT；
背景信息：
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
