靶标：
RNF14
产品别名：
ARA54； HFB30； HRIHFB2038； TRIAD2； RNF14； ring finger protein 14； ring finger protein 14； E3 ubiquitin-protein ligase RNF14； androgen receptor associated protein 54； 环指蛋白14；
背景信息：
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq, Jan 2011],
